Endocrine Abstracts

Background: Primary autoimmune hypophysitis (PAH) is a rare chronic inflammatory condition of the pituitary gland that occurs more commonly in females during pregnancy or in the post-partum period. It is strongly associated with other autoimmune disorders. The various forms of hypophysitis are misdiagnosed as pituitary adenoma in 40% cases.Objective: First of all, we propose to present a case of PAH associated with other autoimmune diseases. Our second a...

Normocalcemic primary hyperparathyroidism (NPH) is characterized by normal total and ionized serum calcium concentrations and consistently elevated PTH levels. These patients have no obvious causes for secondary elevations of PTH, such as renal disease, vitamin D deficiency or malnutrition. The group consisted of 22 postmenopausal women, six premenopausal women, and two men, aged 58±2 years (range 31–77) investigated between 2011 and 2016.Resul...

Introduction: Neuroendocrine tumours (NET) represent ~20% of all primary neoplasms of the lung. Histologic confirmation is important for treatment and prognosis determination. NET are classified according to four subtypes in the lung: typical carcinoid tumour (TC), atypical carcinoid tumour (AC), small cell carcinoma (SCC), and large cell neuroendocrine carcinoma (LCNEC). TC is low-grade, AC is intermediate-grade, and SCC and LCNEC are high-grade malignancies.<p class="abs...

Chronic autoimmune thyroiditis and Graves’ disease (GD) are two forms of autoimmune thyroid disease (AITD).The association of GD or other thyrotoxic forms of autoimmune thyroiditis with one or several toxic nodules is the Marine – Lenhart syndrome (SML). It is a rare pathology with prevalence between 2.7 and 4.1%. Its physiopathology remains complicated and misunderstood, incriminating antithyroidian auto-antibodies such as TSH re...

Introduction: Tertiary hyperparathyroidism (HPT) occurs most commonly in the setting of renal transplant where patients with secondary HPT continue to have elevated PTH levels after receiving a renal allograft. This disease is observed in up to 30% of kidney transplant recipients. This paper will include a case report and a review of epidemiology and pathophysiology, complications and clinical findings, indications for treatment, and the drugs currently available to treat this...

The aim of the study was to assess lipid status in subjects with hypothyroidism (overt and subclinical) and hyperthyroidism. Therefore, we analyzed the relationship between the levels of blood lipids (Lp(a), Apo AI, Apo B, Apo AI/B, total cholesterol (TC), triglyceride (TG), LDL, HDL, LDL) and TSH, FT4, T3, TPOAb concentration. The study groups included 38 subjects with overt hypothyroidism (mean±S.E.M., age 48.6±13.25 years), 30 ...